14/08/23 18:26:38.16
ここにはadult miceでは成功しなかったって書いてあるのに
何故ネイチャーに2012年4月に、adult miceで成功したと論文にして
るのか説明してください。
URLﾘﾝｸ(www.nature.com)
But to earn the name pluripotent, the cells had to show
that they could turn into all cell types ― demonstrated by
injecting fluorescently tagged cells into a mouse embryo.
If the introduced cells are pluripotent, the glowing cells show up
in every tissue of the resultant mouse. This test proved tricky and
required a change in strategy. Hundreds of mice made with help from
mouse-cloning pioneer Teruhiko Wakayama at the University of Yamanashi,
Japan, were only faintly fluorescent. Wakayama, who had initially thought
that the project would probably be a “huge effort in vain”,
suggested stressing fully differentiated cells from newborn mice instead
of those from adult mice. This worked to produce a fully green mouse
embryo.