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Acute otitis media and respiratory viruses.
Bulut Y, Guven M, Otlu B, Yeni?ehirli G, Alada? I, Eyibilen A, Do?ru S.
Eur J Pediatr. 2007 Mar;166(3):223-8. Epub 2006 Sep 12.
Department of Microbiology, Gaziosmanpasa University, Yesilirmak Mah. Bosna Cad.
Mevlana Sitesi, 9 Blok Daire 5, Tokat 60100, Turkey.
URLﾘﾝｸ(www.ncbi.nlm.nih.gov)
The present study was performed to elucidate the clinical outcome, and etiology of acute otitis media (AOM)
in children based on virologic and bacteriologic tests.
The study group consisted of 120 children aged 6 to 144 months with AOM. Middle ear fluid (MEF) was tested
for viral pathogens by reverse transcriptase polymerase chain reaction (RT-PCR)
and for bacteria by gram-staining and culture. Clinical response was assessed on day 2 to 4, 11 to 13, 26 to 28.
Respiratory viruses were isolated in 39 patients (32.5%). Respiratory syncytial virus (RSV)(46.5%) was the most
common virus identified in MEF samples, followed by human rhinovirus (HRV) (25.6%), human coronavirus (HCV) (11.6%),
influenza (IV) type A (9.3%), adenovirus type sub type A (AV) (4%), and parainfluenza (PIV) type-3(2%)
by RT-PCR. In total 69 bacterial species were isolated from 65 (54.8%) of 120 patients.