09/07/10 10:59:35 KSt010l90
今日も劇暇なので、もうひとつ和訳した。
Role of respiratory syncytial virus in acute otitis media: implications for vaccine development.
Patel JA, Nguyen DT, Revai K, Chonmaitree T.
Departments of Pediatrics, University of Texas Medical Branch, Galveston, TX, 77555-0371, United States.
URLﾘﾝｸ(www.pubmedcentral.nih.gov)
We summarize herein the results of various virologic studies of acute otitis media (AOM) conducted at
our site over a 10-year period. Among 566 children with AOM, respiratory syncytial virus (RSV) was
the most common virus identified in either middle ear fluid or nasal wash; it was found in 16% of all children
and 38% of virus-positive children. Seventy-one percent of the children with RSV were 1 year of age or older,
which was significantly older than all other viruses combined (P=0.045). RSV infection was associated with
the common bacterial pathogens causing AOM. Past efforts to develop vaccines for RSV have emphasized
prevention of lower respiratory tract infection in infants, which is a more serious problem but less common
than AOM. Our results suggest that RSV vaccines that work only against infection in older children
may have value in preventing AOM, the most common pediatric disease.