09/07/10 08:51:20 KSt010l90
いけるとこまでやってみるか。
これは日本からのペーパー
Role of respiratory viruses in children with acute otitis media.
Monobe H, Ishibashi T, Nomura Y, Shinogami M, Yano J.
Department of Otolaryngology, Japanese Red Cross Medical Center, Tokyo, Japan
URLﾘﾝｸ(www.ncbi.nlm.nih.gov)
OBJECTIVE:
The role of viral infection in acute otitis media (AOM) has not been
fully elucidated. We determined the presence of various respiratory viruses in
middle ear fluid (MEF) specimens from children with AOM in order to determine
whether viral infection or combined effects of viral and bacterial infection
enhance or prolong the inflammation in the middle ear, thus worsening clinical
outcome.
METHODS:
Multiplex nested reverse transcription-polymerase chain
reactions was carried out to detect influenza A and B viruses, respiratory
syncytial virus (RSV) types A and B, parainfluenza virus types 1, 2, and 3;
rhinovirus; and adenovirus in 93 MEF specimens from 79 children with AOM. And we
examined whether viral infection with or without an identifiable bacterial
infection affect clinical outcomes in AOM. We considered persistent MEF (fluid
accumulation in the middle ear persisting up to 1 month after treatment), early
recurrence of AOM (within 1 month after initial improvement), and recurrent AOM
(more than three recurrences during 6 months of follow up) as indicators for
evaluating clinical outcomes.