23/10/06 11:49:45.45 OI1f5IvR0.net
URLﾘﾝｸ(www.nature.com)
Article l Open access l Published: 10 June 2023
Human skin gas profile of individuals with the people allergic to me phenomenon
Yoshika Sekine, Daisuke Oikawa & Michihito Todaka
Scientific Reports volume 13, Article number: 9471 (2023) Cite this article
URLﾘﾝｸ(www.nature.com)
Abstract
Recent studies have shown that some people claim that their skin gases provoke
allergy-like reactions in people in their near vicinity. Such a phenomenon or symptom is
called ‘people allergic to me (PATM)’. Although numerous people suffer from PATM,
the actual conditions are unknown. The aim of this study was to investigate the characteristics
of human skin profiles in patients with PATM by measuring the dermal emission fluxes of
75 skin gases using passive flux sampler and gas chromatography/mass spectrometry.
We found common features in the human skin gas profiles of 20 subjects with PATM,
with a significant difference from those of 24 non-PATM subjects: greater emissions of
petrochemicals, organosulfur compounds, and some aldehydes and lower emissions of aroma compounds and others.
The ratio of toluene to benzaldehyde is considered a vital sign that suggests the fundamental of PATM.
These findings indicate that PATM is a medically unexplained phenomenon or symptom worthy of further research,
which requires an interdisciplinary approach.